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. 2022 May 30;10:853056. doi: 10.3389/fpubh.2022.853056

Table 2.

Study characteristics.

Studies Country Intervention (essential oils) Application Control Sample size (n) Duration Scale
Ayik et al. (31) Turkey Lavender oil (Lavandula Hybrida)
+ almond oil: 5%
Massage Standard nursing care 80 10 min/day, per 2 days SAI (+)
Beyliklioglu et al. (32) Turkey Lavender oil Inhalation Routine care 80 20 min, per 1 day SAI (+)
Corner et al. (33) America A blend of lavender (Lavendula angustifolia), rosewood (Aniba rosaerodora), lemon (Citrus limonum), rose (Rosa damascena) and valerian (Valeriana officinalis) oilsat a ratio of 43:29:17:7:4
(2) carrier oil group: sweet almond oil
Massage None 52 30 min/week, per 8 weeks HADS (-)
Deng et al. (34) China A blend of lavender, bergamot and geranium oils at a ratio of 1:2:3 Inhalation Usual care 80 30 min, twice/day VAS (+)
Duluklu et al. (35) Turkey Lavender oil Inhalation Routine care 30 15 min/day OAI-23 (+)
Graham et al. (36) Australia A blend of lavender, bergamot and cedarwood oils at a ratio of 2:1:1 Inhalation (1) fractionated low-grade essential oils
(2) pure essential oils
(3) Carrier oil
313 15–20 min during radiotherapy HADS (-)
Noh and Park (38) Korea A blend of mandarin, black pepper, pine and tea tree essential oils at a ratio of 1:1:1:1 Massage None 63 30 min/session,
3 times/week per
6 weeks
HADS (+)
Ovayolu et al. (39) Turkey (1) fragrance: a blend of lavender, mint, chamomile, jasmine, violet, rosemary and eucalyptus oils at a ratio of 2:2:2:1:1:1:1
(2) 35 min massage with olive oil
(3) 35 min massage with aromatherapy oils
(1) Inhalation
(2) Massage
(3) Massage
Routine care 280 3 times/week RSCL-Psychology (+)
Ozkaraman et al. (40) Turkey (1) lavender (Lavandula Hybrida)
(2) tea tree oil
Inhalation None 70 5 min/day SAI (-)
Pimenta et al. (41) Brazil (1) 10 mg diazepam (2) Citrus aurantium oil Inhalation Saline solution 42 30 min SAI (+)
Santosh et al. (42) India Lavender oil Massage and Inhalation None 60 10 min/h, during chemotherapy BAI (+)
Serfaty et al. (37) UK A choice of 20 essential oils Massage CBT 36 1 h/session, 8 sessions/10 weeks POMS (-)
Soden et al. (43) UK (1) Lavender oil and an inert carrier oil
(2) an inert carrier oil
Massage None 42 30 min/week, per 4 weeks HADS (-)
RSCL (-)
Wilcock et al. (44) UK Lavender + chamomile + sweet almond carrier oil Massage Day care 29 30 min/week, per 4 weeks POMS (-)
Wilkinson et al. (46) UK Roman chamomile oil + sweet almond carrier oil Massage Carrier oil (sweet almond oil) 46 3 full-body massages per 3 weeks SAI (-)
RSCL (-)
Wilkinson et al. (45) UK Roman chamomile oil + sweet almond carrier oil Massage Carrier oil (sweet almond oil) 87 3 full-body massages per 3 weeks SAI (-)
RSCL (-)
Wilkinson et al. (47) UK A choice of 20 essential oils Massage Usual care 221 1 h/week, per 4 weeks SAI (+)
CES-D (-)