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. 2022 Mar 11;119(10):167–174. doi: 10.3238/arztebl.m2022.0147

Table 4. Parsimonious model of the multiple ordinal logistic regression*1.

Level OR [95% CI] p-value
Age Continuous 1.003 [0.996; 1.010] 0.45
Sex Female 1.805 [1.454; 2.241] < 0.001
Male Reference
Education level*2 Metric 1.147 [1.057; 1.245] 0.001
Nursing home resident Yes 0.087 [0.046; 0.165] < 0.001
No Reference
SCQ-D*3 Continuous 1.096 [1.058; 1.137] < 0.001
Hospitalized during acute COVID-19*4 Yes 2.014 [1.538; 2.637] < 0.001
No Reference
Need for analgesics during acute COVID-19*5 Yes 1.704 [1.186; 2.446] 0.004
No Reference

*1 Parsimonious model after stepwise backward selection of the potential predicting variables for post-COVID-19. The outcome variable comprised three categories (1, no symptoms; 2, symptom duration < 12 weeks; 3, symptom duration = 12 weeks) with post-COVID-19 (symptom duration ≥ 12 weeks) as response (n = 1459; imputed data set with 500 imputations).

*2 Only one parameter was estimated in a linear coding of the six different educational levels.

*3 Interpretation of the OR: with each increase of one point on the 45-point scale of the SCQ-D, the likelihood of developing post-COVID-19 rises by 9.6%. In other words, the higher the overall burden of ?comorbidities (measured on the SCQ-D), the greater the likelihood of developing post-COVID-19.

*4 Interpretation of the OR: Study participants who had to be hospitalized for treatment during the acute phase of COVID-19 have a 2.01 times greater likelihood of developing post-COVID-19 than those who were not hospitalized. In other words, their risk of developing post-COVID-19 is 101% higher.

*5 Interpretation of the OR: Study participants who had to take analgesics during the acute phase of COVID-19 had a 1.7 times greater likelihood of developing p ost-COVID-19 than those who did not have to take analgesics. In other words, their risk of developing post-COVID-19 is 70% higher. This does not mean that the consumption of analgesics causes the higher risk; rather, it is a surrogate for the severity of the acute disease.

95% CI, 95% confidence interval; OR, odds ratio;

SCQ-D, Self-Administered Comorbidity Questionnaire, German version