Table 4. Parsimonious model of the multiple ordinal logistic regression*1.
Level | OR | [95% CI] | p-value | |
Age | Continuous | 1.003 | [0.996; 1.010] | 0.45 |
Sex | Female | 1.805 | [1.454; 2.241] | < 0.001 |
Male | Reference | |||
Education level*2 | Metric | 1.147 | [1.057; 1.245] | 0.001 |
Nursing home resident | Yes | 0.087 | [0.046; 0.165] | < 0.001 |
No | Reference | |||
SCQ-D*3 | Continuous | 1.096 | [1.058; 1.137] | < 0.001 |
Hospitalized during acute COVID-19*4 | Yes | 2.014 | [1.538; 2.637] | < 0.001 |
No | Reference | |||
Need for analgesics during acute COVID-19*5 | Yes | 1.704 | [1.186; 2.446] | 0.004 |
No | Reference |
*1 Parsimonious model after stepwise backward selection of the potential predicting variables for post-COVID-19. The outcome variable comprised three categories (1, no symptoms; 2, symptom duration < 12 weeks; 3, symptom duration = 12 weeks) with post-COVID-19 (symptom duration ≥ 12 weeks) as response (n = 1459; imputed data set with 500 imputations).
*2 Only one parameter was estimated in a linear coding of the six different educational levels.
*3 Interpretation of the OR: with each increase of one point on the 45-point scale of the SCQ-D, the likelihood of developing post-COVID-19 rises by 9.6%. In other words, the higher the overall burden of ?comorbidities (measured on the SCQ-D), the greater the likelihood of developing post-COVID-19.
*4 Interpretation of the OR: Study participants who had to be hospitalized for treatment during the acute phase of COVID-19 have a 2.01 times greater likelihood of developing post-COVID-19 than those who were not hospitalized. In other words, their risk of developing post-COVID-19 is 101% higher.
*5 Interpretation of the OR: Study participants who had to take analgesics during the acute phase of COVID-19 had a 1.7 times greater likelihood of developing p ost-COVID-19 than those who did not have to take analgesics. In other words, their risk of developing post-COVID-19 is 70% higher. This does not mean that the consumption of analgesics causes the higher risk; rather, it is a surrogate for the severity of the acute disease.
95% CI, 95% confidence interval; OR, odds ratio;
SCQ-D, Self-Administered Comorbidity Questionnaire, German version