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. 2022 Mar 11;119(10):167–174. doi: 10.3238/arztebl.m2022.0147

eTable 3. Medications taken on a regular basis (for at least 12 months).

Total study population p-value*1 Post-COVID-19 (Symptom duration ≥ 12 weeks) p-value*1
No symptoms/ symptoms < 12 weeks n = 739 Symptoms ≥ 12 weeks(post-COVID-19) n = 720 Not hospitalized n = 588 Hospitalized n = 127
ACE-I and ARB 108 (14.6) 172 (23.9) < 0.001 108 (18.4) 63 (49.6) < 0.001
Other antihypertensives 118 (16.0) 159 (22.1) 0.011 98 (16.7) 61 (48.0) < 0.001
Metformin 20 (2.7) 40 (5.6) 0.008 21 (3.6) 19 (15.0) < 0.001
Other antidiabetics 18 (2.4) 30 (4.2) 0.077 16 (2.7) 14 (11.0) < 0.001
Diuretics 51 (6.9) 79 (11.0) 0.023 39 (6.5) 41 (32.3) < 0.001
Lung inhalers 33 (4.5) 71 (9.9) < 0.001 47 (8.0) 22 (17.3) < 0.001
Cholesterol-reducing drugs 53 (7.2) 90 (12.5) 0.002 53 (9.0) 37 (29.1) < 0.001
ASA 100 51 (6.9) 83 (11.5) 0.006 49 (8.3) 33 (26.0) < 0.001
Anticoagulants 36 (4.9) 44 (6.1) 0.584 16 (2.7) 28 (22.0) < 0.001
Opiates and morphines 11 (1.5) 16 (2.2) 0.498 9 (1.5) 7 (5.5) < 0.001
Other analgesics 59 (8.0) 83 (11.5) 0.041 58 (9.9) 25 (19.7) < 0.001
Vitamin D 104 (14.1) 157 (21.8) < 0.001 118 (20.1) 38 (29.9) 0.018
Antidepressants*3 12 (1.6) 38 (5.3) < 0.001 28 (4.8) 10 (7.9) 0.156
Thyroid medications*3 68 (9.2) 119 (15.3) < 0.001 93 (15.8) 16 (12.6) 0.360
Homeopathic preparations*3 7 (0.9) 19 (2.6) 0.015 14 (2.4) 5 (3.9) 0.323
Proton pump inhibitors*3 15 (2.0) 25 (3.5) 0.092 20 (3.4) 5 (3.9) 0.766
Contraceptives*3 16 (2.2) 21 (2.9) 0.407 20 (3.4) 1 (0.8) 0.149*2
Vitamins and supplements*3 26 (3.5) 35 (4.9) 0.200 27 (4.6) 8 (6.3) 0.419
Other medications*3 57 (7.7) 86 (11.9) 0.007 59 (10.0) 27 (21.3) < 0.001

Absolute and relative frequencies are presented as n (%). Information on hospitalization was missing for five patients in the post-COVID-19 group.

ACE-I, Angiotensin-converting enzyme inhibitors; ARB, angiotensin receptor blocker; ASA 100, acetylsalicylic acid 100 milligram

*1 Chi-square tests were used to calculate p-values unless otherwise indicated. *2 Fisher’s exact test. *3 Information from the optional text boxes