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. 2022 Mar 11;119(10):167–174. doi: 10.3238/arztebl.m2022.0147

eTable 4. Treatment during the acute phase of COVID-19.

Total study population p-value*1 Post-COVID-19 (Symptom duration ≥ 12 Wochen) p-value*1
No symptoms/ symptoms < 12 weeks n = 739 Symptoms ≥ 12 weeks(post-COVID-19) n = 720 Not hospitalized n = 588 Hospitalized n = 127
Hospitalization for acute COVID-19
 Not hospitalized 685 (92.7) 588 (81.7) < 0.001 588 n. a. n.d.
 Hospitalized*2 48 (6.5) 127 (17.6) n.d. 127
 Intensive care unit 6 (0.8) 25 (3.5) < 0.001 n.d. 25
 Mechanical ventilation 5 (0.7) 20 (2.8) n.d. 20
Medication for acute Covid-19
 No 576 (77.9) 412 (57.2) < 0.001 386 (65.6) 21 (16.7) < 0.001
 Yes 156 (21.1) 295 (41.0) 196 (33.3) 99 (78.0)
 Antibiotics 54 (7.3) 100 (13.9) < 0.001 43 (7.3) 57 (44.9) < 0.001
 Zinc/selenium/vitamin D 25 (3.4) 61 (8.5) < 0.001 49 (8.3) 12 (9.4) 0.726
 Anticoagulation 20 (2.7) 63 (8.8) < 0.001 22 (3.7) 41 (32.3) < 0.001
 Cortisone 9 (1.2) 39 (5.4) < 0.001 26 (4.4) 13 (10.2) 0.012
 Analgesics *3 58 (7.8) 85 (11.8) 0.013 75 (12.8) 10 (7.9) 0.133
 Common cold remedies *3 10 (1.4) 18 (2.5) 0.128 16 (2.7) 2 (1.6) 0.554*4
 Homeopathic preparations *3 3 (0.4) 3 (0.4) 1.000*4 3 (0.5) 0 (0) 1.000*4
 Other vitamins/trace elements *3 5 (0.7) 10 (1.4) 0.202 10 (1.7) 0 (0) 0.223*4
 Lung inhalers *3 5 (0.7) 18 (2.5) 0.006 15 (2.6) 3 (2.4) 1.000*4
 Others *3 17 (2.3) 41 (5.7) < 0.001 24 (4.1) 17 (13.4) < 0.001

Absolute and relative frequencies are presented as n (%). Information on hospitalization was missing for five patients in the post-COVID-19 group.

*1 The chi-square test was used to calculate p-values unless otherwise indicated. *2 Including intensive care unit and mechanical ventilation.

*3 Information from the optional text boxes.

*4 Fisher’s exact test

n.a., not applicable