eTable 8. Sensitivity analysis of the secondary endpoints in the per-protocol population.
| Group comparison Delegation − Standard | |||
| Estimated difference*1 | 95% confidence interval | Direction | |
| CRP (mg/L)*2 | 0.1 | [−0.1; 0.2] | ↓ |
| Disease activity (NRS) | −0.1 | [−0.5; 0.2] | ↑ |
| Pain intensity (NRS) | −0.2 | [−0.6; 0.1] | ↑ |
| Fatigue (NRS) | −0.2 | [−0.5; 0.2] | ↑ |
| Sleep disturbances (NRS) | −0.3 | [−0.7; 0.1] | ↑ |
| Duration of morning stiffness (minutes) | 0.7 | [−4.1; 5.5] | ↓ |
| Depression (PHQ-2) | −0.1 | [−0.3; 0.2] | ↑ |
| Functional capacity (FFbH) | −0.2 | [−2.8; 2.5] | ↑ |
| Physical activity (PRISCUS-PAQ) | 1.6 | [−0.1; 3.3] | ↓ |
*1 estimated using a linear mixed model for each endpoint with adjustment for patient age and sex,respective baseline value, and center (random effect)
*2 given the skewness of the distribution, median and interquartile range (Q25-Q75) of changes are presented, and the model is calculated with log CRP.
CRP, C-reactive protein; FFbH: Hanover Functional Status Questionnaire (0–100);
NRS, Numeric Rating Scale (0–10);
PAQ: Physical Activity Questionnaire (≥168 MET hours/week [MET, metabolic equivalent]);
PHQ-2, Patient Health Questionnaire 2 Items (0–6);
↑ indicates the advantage of the team-based form of care, ↓ advantage of standard care