Table 2. Analysis of the primary endpoints.

	Change after one year*1 per group		Group comparison
Endpoint	Team-basedform of care	Standard care	Team-based − Standard
	Observedmean value (SD)	Observedmean value (SD)	Estimated difference[95% confidence interval]	p value	D
DAS28	−0.14(1.07)	0.04(1.15)	−0.19[−0.36; −0.02]*2	< 0.001*4	↑
EQ-5D-5L	0.02(0.21)	0.01 (0.23)	0.02[−0.02; 0.05]*3	0.285	↑

*¹ final value – initial value

*² estimated using a mixed linear model in der per protocol population with adjustment for patient sex,

baseline DAS28 score, type of rheumatoid disease, and center (random effect)

*³ estimated using a linear mixed model in intention-to-treat population with adjustment for patient age and sex,

EQ-5D-5L score at baseline, type of rheumatic disease, and center (random effect)

*⁴ p value from test for non-inferiority, p = 0.025 in test for superiority

DAS28, Disease Activity Score with 28 joints; EQ-5D-5L, EuroQol in 5 dimensions and 5 response levels; D, direction of the estimated difference;

SD, standard deviation; ↑ indicates advantage of team-based form of care.