eTable 3. Calculation procedures of the cost types included in the total cost estimate and source of the reference cost amounts used.

Resource	Base unit	Cost evaluation
Specialist outpatient consultations	Number of visits to the doctor, broken down by specialist groups	Multiplied by the mean value of contact costs for each specialist group (cf. Bock et al. 2015 [e3])
Drug prescriptions	Type and number of drugs	Multiplied by the current inflation-adjusted prices for fixed-price drugs (DIMDI, 2021); otherwise, by reference costs provided by BARMER Health Insurance Fund
Outpatient surgical procedures/day care unit, inpatient stays in hospital, including psychiatric facilities	Number and duration of hospital stays (i.e. overnight stays) and/oroutpatient surgical procedures, stays in day care units and/or psychiatric facilities	Excluded from cost estimation due to too non-specific data
Healthcare services, including remedies	Type and number of services	Multiplied either by statutory health insurance reimbursement rates (if available) or by researched cost rates and estimates