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. 2022 Jun 21;2022(6):CD015017. doi: 10.1002/14651858.CD015017.pub3

Risk of bias for analysis 1.6 Viral clearance at day 3.

Study Bias
Randomisation process Deviations from intended interventions Missing outcome data Measurement of the outcome Selection of the reported results Overall
Authors' judgement Support for judgement Authors' judgement Support for judgement Authors' judgement Support for judgement Authors' judgement Support for judgement Authors' judgement Support for judgement Authors' judgement Support for judgement
Subgroup 1.6.1 Moderate disease (WHO 4 to 5)
Mohan 2021 Low risk of bias Centralized telephone‐based randomization. There are no baseline differences that would suggest a problem with randomization. Low risk of bias Both participants and those delivering the intervention were not aware of the intervention received and the analysis was appropriate. Low risk of bias Reasons for missing outcome data were described and appropriate in the context of this outcome (only RT‐PCR positive people at baseline). 11/125 participants were no longer hospitalized at day 7 and missing for analysis. Low risk of bias Outcome assessors were not aware of the intervention received. Knowledge of intervention received could not have affected outcome measurement. Low risk of bias The protocol was prospectively registered and the outcome in the journal publication was reported as registered. Low risk of bias Due to low risk of bias in all domains.