Table 2.
Association Between Serum Asprosin and Other Covariates in Patients with Type 2 Diabetes
| 变量 | Total | Male | Female | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pearson Correlation | Multiple Linear Regression | Pearson Correlation | Multiple Linear Regression | Pearson Correlation | Multiple Linear Regression | |||||||
| r | P | Standardized β | P | r | P | Standardized β | P | r | P | Standardized β | P | |
| *Duration (y) | −0.051 | 0.257 | – | – | −0.018 | 0.756 | – | – | −0.024 | 0.738 | – | – |
| Age (y) | −0.015 | 0.739 | – | – | 0.030 | 0.610 | – | – | 0.032 | 0.655 | – | – |
| SBP (mmHg) | 0.064 | 0.153 | – | – | 0.110 | 0.058 | – | – | 0.055 | 0.439 | – | – |
| DBP (mmHg) | 0.123 | 0.006 | – | – | 0.096 | 0.097 | – | – | 0.089 | 0.210 | – | – |
| BMI (kg/m2) | 0.304 | <0.001 | 0.200 | <0.001 | 0.307 | <0.001 | 0.234 | <0.001 | 0.272 | 0.000 | 0.224 | 0.001 |
| TC (mmol/l) | −0.028 | 0.536 | – | – | −0.032 | 0.580 | – | – | 0.025 | 0.720 | – | – |
| TG* (mmol/l) | 0.314 | 0.000 | 0.116 | 0.005 | 0.265 | <0.001 | 0.396 | 0.000 | 0.189 | 0.005 | ||
| LDL-C (mmol/l) | −0.097 | 0.030 | −0.081 | 0.162 | - | - | −0.089 | 0.212 | - | - | ||
| HDL-C (mmol/l) | −0.187 | <0.001 | −0.086 | 0.035 | −0.142 | 0.014 | −0.152 | 0.032 | ||||
| FPG (mmol/l) | −0.097 | 0.031 | −0.109 | 0.007 | −0.165 | 0.004 | −0.147 | 0.005 | −0.018 | 0.799 | - | - |
| HbA1c (%) | −0.108 | 0.016 | −0.163 | 0.005 | −0.041 | 0.561 | - | - | ||||
| AST* (IU/L) | 0.192 | <0.001 | 0.110 | 0.008 | 0.220 | <0.001 | 0.139 | 0.012 | 0.165 | 0.019 | ||
| ALT* (IU/L) | 0.197 | <0.001 | 0.188 | 0.001 | 0.130 | 0.067 | - | - | ||||
| Scr* (umol/l) | 0.384 | <0.001 | 0.296 | <0.001 | 0.391 | 0.000 | 0.217 | 0.043 | ||||
| ACR* (mg/g) | 0.212 | <0.001 | 0.109 | 0.011 | 0.208 | <0.001 | 0.197 | 0.004 | 0.285 | 0.000 | 0.238 | 0.002 |
| eGFR (mL/min/1.73 m2) | −0.378 | <0.001 | −0.335 | <0.001 | −0.319 | <0.001 | −0.294 | <0.001 | −0.364 | 0.000 | −0.492 | <0.001 |
Note: *Spearman correlation analysis was used for skewness distribution.
Abbreviations: BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; AST, aspartate aminotransferase; ALT, alanine aminotransferase; TG, triglycerides; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; FPG, fasting blood glucose; PPG, blood glucose at 2 hours after meals; HbA1c, glycosylated haemoglobin; CRE, creatinine; eGFR, estimated glomerular filtration rate; ACR, albumin-to-creatinine ratio.