Table 1.
Superantigen Gene Profiling of Staphylococcus aureus Isolates from BP Lesions
Staphylococcal SAgs1 |
|||||||
---|---|---|---|---|---|---|---|
G | I | M | N | O | U | TSST-1 | |
| |||||||
No. (%) | 212 (100) | 21 (100) | 23 (9.5) | 21 (100) | 21 (100) | 193 (90.4) | 21 (100) |
Abbreviations: BP, bullous pemphigoid; EGC, enterotoxin gene cluster; No., number; SAg, superantigen; TSST-1, toxic shock syndrome toxin-1.
Evaluated on isolated colonies by PCR using primers specific for EGC toxins and TSST-1.
Of 28 patients with BP, TSST-1+ S. aureus was isolated from 22; 1 sample had insufficient RNA extracted, leaving 21 samples.
Two separate individuals either lack U or express M, leaving 17 patients with BP with 100% expression of the EGC plus TSST-1.