Table 2.
Antibiotic Treatment of Patients with BP Eliminates Lesional Staphylococcus aureus Colonization and Is Associated with a Reduction in Disease Severity
| Patient ID | Sex/Age (y) | Before Referral1 (Drug, Daily Dose, Duration) | After Enrollment (Drug, Daily Dose) | BPDAI2 Enrollment/Follow-Up (Days Elapsed) | % Decline BPDAI3 |
|---|---|---|---|---|---|
| 758 | M/67.2 | Prednisone, 60 mg, 39 d; Mycophenolate, 3 g, 39 d |
Prednisone, 40 mg; Clindamycin, 1.35 g; Mycophenolate, 1g |
173/97 (23) | 44 |
| 781 | F/61.5 | Triamcinalone, 0.1% ointment | Clindamycin, 1.35 g | 92/44 (25) | 52 |
| 703 | F/87.1 | Betamethasone, 0.05% ointment | Doxycycline, 200 mg | 59/50 (21) | 15 |
| 807 | M/74.3 | Triamcinalone, 0.1% ointment | Doxycycline, 200 mg | 43/37 (27) | 14 |
Abbreviations: BP, bullous pemphigoid; BPDAI, Bullous Pemphigoid Disease Area Index; F, female; ID, identification; M, male.
S. aureus was isolated from lesional swabs obtained from patients with BP on the date of enrollment.
Medications prescribed by the referring physician before their initial visit to University of Iowa Hospitals & Clinics.
Disease severity was scored using the BPDAI on the date of enrollment and at the next routine visit; the number of days elapsed is indicated in the parentheses.
The percentage decline in BPDAI = (BPDAI enrollment / [BPDAI at enrollment − BPDAI at follow-up]) × 100.