Table 4.

The expression levels of VEGF, HIF‐1α, and PD‐L1 in NCI‐H838 cells (mean ± SD, n = 3)

Treatment	VEGF	HIF‐1α	PD‐L1
Normoxia	0.425 ± 0.080	0.387 ± 0.031	0.517 ± 0.063
Hypoxia	0.564 ± 0.073 a	0.558 ± 0.042 a	0.802 ± 0.058 a
Normoxia + rhEPO 2 U/ml	0.432 ± 0.053	0.404 ± 0.017 b	0.550 ± 0.024 b
Hypoxia + rhEPO 2 U/ml	0.495 ± 0.034 b	0.461 ± 0.033 a , b , c	0.753 ± 0.062 a , c
Normoxia + rhEPO 8 U/ml	0.452 ± 0.057	0.410 ± 0.039 b	0.524 ± 0.091 b , d
Hypoxia + rhEPO 8 U/ml	0.474 ± 0.061 b	0.449 ± 0.021 a , b	0.782 ± 0.051 a , c , e

^a p < 0.05 versus Normoxia;

^b p < 0.05 versus Hypoxia;

^c p < 0.05 versus Normoxia + rhEPO 2 U/ml;

^d p < 0.05 versus Hypoxia + rhEPO 2 U/ml;

^e p < 0.05 versus Normoxia + rhEPO 8 U/ml.