Figure 4.

Serum lactate dehydrogenase (LDH) activity improved prediction of death in acetaminophen-induced acute liver failure. Total LDH activity and alanine aminotransferase were measured in serum from all nonsurvivors and survivors on study days 1 and 3. Model for end-stage liver disease (MELD) scores were also obtained when available (n = 20 for survivors and 29 for nonsurvivors). A, Receiver operating characteristic (ROC) curves for LDH, MELD, and MELD-LDH on day 1. B, ROC curves showing sensitivity and specificity for LDH, MELD, and MELD-LDH on day 3.