Table 4.
Top 20 Proteins Decreased in Serum in ALF Patients Versus Control Subjects
| Protein | Log2FC | Adjusted p-value |
|---|---|---|
| NARS | −6.15 | 1.3 × 10−2 |
| CYP3A4 | −5.64 | 7.2 × 10−8 |
| OSGEP | −5.33 | 2.3 × 10−10 |
| LRRC59 | −5.27 | 3.4 × 10−2 |
| F7 | −5.09 | 1.5 × 10−9 |
| SPP2 | −4.84 | 7.4 × 10−9 |
| CUL4A | −4.71 | 6.4 × 10−4 |
| INHBC | −4.64 | 5.7 × 10−12 |
| RARRES2 | −4.62 | 1.3 × 10−11 |
| IGLC6 | −4.46 | 4.8 × 10−13 |
| VTN | −4.40 | 1.0 × 10−6 |
| APOC4 | −4.28 | 8.0 × 10−9 |
| HPSE | −4.23 | 2.5 × 10−6 |
| CFHR5 | −4.23 | 1.4 × 10−10 |
| PROC | −4.21 | 3.5 × 10−12 |
| PGP | −4.09 | 5.5 × 10−7 |
| EIF2S2 | −4.01 | 2.4 × 10−2 |
| CFHR4 | −3.79 | 3.4 × 10−8 |
| FARP1 | −3.71 | 1.9 × 10−5 |
| APOF | −3.70 | 1.7 × 10−6 |
Abbreviations: Log2FC, log base 2 fold-change; ALF, acute liver failure