TABLE 3.

Interrupted time series results for change in outcome after COVID-19 containment measures. Segmented regression model parameter estimates, 95% CI and p-value for (a) weekly hospitalization rates (b) mean length of stay and (c) weekly percent discharged home in Tuscany between January and July. Changes in acute myocardial infarction, stroke and heart failure hospitalizations during COVID-19 pandemic in Tuscany—an interrupted time series study, Tuscany, Italy, 2020.

	Level change			Trend change
	Effect	95% CI	p-value	Effect	95% CI	p-value
Hospitalization rate (per 100000)
All Inpatient	−182	(−235, −130)	<0.001	1.04	(−8.16, 10.24)	0.826
Urgent Care	−39	(−51.1, −26.0)	<0.001	0.67	(−1.99, 3.34)	0.624
AMI	−1.31	(−1.98, −0.66)	<0.001	−0.04	(−0.20, 0.12)	0.635
Stroke	−1.51	(−2.57, −0.44)	0.008	0.05	(−0.13, 0.24)	0.564
Heart Failure	−8.71	(−11.12, −6.29)	<0.001	0.33	(−0.09, 0.75)	0.129
Average length of stay (days)
AMI	0.63	(−0.31, 1.57)	0.183	0.07	(−0.11, 0.25)	0.427
Stroke	0.82	(−0.95, 2.58)	0.355	−0.01	(−0.32, 0.29)	0.924
Heart Failure	0.01	(−0.69, 0.71)	0.981	−0.06	(−0.19, 0.06)	0.290
In-hospital mortality (%)
AMI	−1.39	(−4.73, 1.94)	0.406	−0.17	(−0.75, 0.40)	0.548
Stroke	0.27	(−1.45, 1.98)	0.763	0.04	(−0.28, 0.37)	0.794
Heart Failure	2.43	(−0.73, 5.60)	0.138	−0.36	(−0.91, 0.19)	0.207