S20	S15 AND S18 Published 20110901‐
S19	S15 AND S18
S18	S16 OR S17
S17	TI antiepilep* or anti‐epilep* or anticonvuls* or anti‐convuls* or AED or AEDs or Acetazolamide or Alodorm or Antilepsin or Arem or Ativan or Barbexaclone or Beclamide or Brivaracetam or Carbagen or Carbamazepine or Celontin or Cerebyx or Chlonazepam or Chloracon or Cloazepam or Clobazam or Clonazepamum or Clonex or Clonopin or Clorazepate or Convulex or Depacon or Depak* or Depamide or Desitin or Diacomit or Diamox or Diastat or Diazepam or Dilantin or Diphenin* or Diphenylhydantoin or Divalpr* or Dormicum or Ecovia or Emeside or Epanutin or Epiject or Epilim or Episenta or Epival or Eptoin or Ergenyl or Erimin or Eslicarbazepine or Ethadione or Ethosuximide or Ethotoin or Ethylphenacemide or Exalief or Excegran or Ezogabine or Fanatrex or Felbamate or Felbatol or Fosphenytoin or Frisium or Fycompa or Gabapentin or Gabarone or Gabitril or Gabrene or Ganaxolone or Garene or Gralise or Halogabide or Halogenide or Hibicon or Hypnovel or Iktorivil or Inovelon or Insoma or Intensl or Keppra or Klonopin or Kriadex or Lacosamide or Lamict* or Lamitor or Lamitrin or Lamogine or Lamotrigine or Lamotrine or Landsen or Levetiracetam or Liskantin or Loraz or Lorazepam or Losigamone or Luminal or Lyrica or Mebaral or Mephenytoin or Mephobarbit* or Mephyltaletten or Mesantoin or Mesuximide or Methazolamide or Methsuximide or Methylphenobarbit* or Midazolam or Mogadon or Mylepsinum or Mysoline or Neogab or Neptazane or Neurontin or Nimetazepam or Nitrados or Nitrazadon or Nitrazepam or Normison or Novo‐Clopate or Nupentin or Nydrane or Onfi or Orfiril or Orlept or Ormodon or Ospolot or Oxcarbazepine or Pacisyn or Paraldehyde or Paramethadione or Paxadorm or Paxam or Peganone or Perampanel or Petinutin or Petril or Phemiton or Phenacemide or Pheneturide or Phenobarbit* or Phensuximide or Phenytek or Phenytoin or Posedrine or Potiga or Pregabalin or Primidone or Prodilantin or Progabide or Prominal or Prysoline or Ravotril or Remacemide or Remnos or Resimatil or Restoril or Retigabine or Riv?tril or Rufinamide or Sabril or Seclar or Selenica or Seletracetam or Sertan or Somnite or Stavzor or Stedesa or Stiripentol or Sulthiam* or Sultiam* or Talampanel or Tegretol or Temazepam or Temesta or Teril or Tiagabine or Timonil or Topamax or Topiramate or Tranxene or Tridione or Trileptal or Trimethadione or Trobalt or Urbanol or Valance or Valcote or Valium or Valnoctamide or Valparin or Valpro* or Versed or Vigabatrin or Vimpat or Zalkote or Zarontin or Zebinix or Zonegran or Zonisamide
S16	MM "Anticonvulsive Drugs" OR MM "Carbamazepine" OR MM "Chloral Hydrate" OR MM "Clonazepam" OR MM "Diphenylhydantoin" OR MM "Nitrazepam" OR MM "Oxazepam" OR MM "Pentobarbital" OR MM "Phenobarbital" OR MM "Pregabalin" OR MM "Primidone" OR MM "Valproic Acid"
S15	S10 AND S13 AND S14
S14	TI ( (randomiz* OR randomis* OR controlled OR placebo OR blind* OR unblind* OR "parallel group" OR crossover OR "cross over" OR cluster OR "head to head") N2 (trial OR method OR procedure OR study) ) OR AB ( (randomiz* OR randomis* OR controlled OR placebo OR blind* OR unblind* OR "parallel group" OR crossover OR "cross over" OR cluster OR "head to head") N2 (trial OR method OR procedure OR study) )
S13	S11 OR S12
S12	epilep* OR seizure* OR convuls*
S11	MM "Epilepsy" OR MM "Epileptic Seizures" OR MM "Experimental Epilepsy" OR MM "Grand Mal Seizures" OR MM "Petit Mal Seizures" OR MM "Status Epilepticus"
S10	S1 OR S2 OR S3 OR S4 OR S5 OR S6 OR S7 OR S8 OR S9
S9	Rett* syndrome or Lennox Gastaut syndrome or Down* syndrome or Angelman* syndrome or West* syndrome
S8	autistic or autism or cerebral palsy or fragile X syndrome
S7	development* disab* or multipl* handicap* or cognitive impairment or tuberous sclerosis
S6	intellect* disab* or intellect* impair* or intellect* handicap*
S5	mental* disab* or mental* retard* or mental* deficien* or mental* handicap* or mental* incapacity or mental* disorder*
S4	learning disab* or learning difficult* or learning problem* or learning disorder* or learning handicap*
S3	DE "autism" or "cerebral palsy" or "downs syndrome"
S2	DE "learning disabilities" or "learning disorders" or "mental disorders" or "rett syndrome"
S1	DE "cognitive impairment" or "mental retardation" or "developmental disabilities" or "fragile x syndrome"