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(a) Micro-CT images of a periodontal defect and the design and adaptation ratio of a site-specific scaffold for regeneration. (b) SEM images evidencing dense formation of fibrous tissue for the fiber-guiding scaffolds and collagen-like fibers anchorage on the dentin structure. (c) Histological analysis (H&E) comparing tissue morphologies and organization of random and fiber-guiding scaffolds. Adapted from.185
