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. Author manuscript; available in PMC: 2023 Jan 1.
Published in final edited form as: Int Mater Rev. 2021 Jul 5;67(4):347–384. doi: 10.1080/09506608.2021.1946236

Figure 6.

Figure 6.

Schematic illustration of the spatially designed and functionally graded (FGM) periodontal membrane. (a) Membrane placed in a guided bone regeneration scenario and (b) details of the core-layer (CL) and the functional surface-layers (SL) interfacing bone (nano-hydroxyapatite, n-HAp) and epithelial (metronidazole, MET) tissues. Note the chemical composition step-wise grading from the CL to SLs, i.e., polymer content decreased, and protein content increased. (c) Cross-section SEM micrographs of the FGM processed via multilayering electrospinning. Adapted from.42