Table 1.
Patients’ demographics and radiologic characteristics.
| ADMSC (n = 13) |
Control (n = 13) |
P value | |
|---|---|---|---|
| Age, years | 58.3 ± 6.4 | 59.1 ± 5.9 | .754a |
| Sex, female/male, n | 11/2 | 8/5 | .378d |
| Operated side, right/left, n | 8/5 | 7/6 | >.999c |
| BMI, kg/m2 | 25.6 ± 2.7 | 25.8 ± 2.6 | .887a |
| Smoking status, n | >.999d | ||
| Never smoked | 11 | 11 | |
| Current smoker | 2 | 2 | |
| Comorbidities, n | .883c | ||
| None | 4 | 5 | |
| HTN/DM/dyslipidemia | 7/3/1 | 6/1/2 | |
| Range of motion, ° | |||
| Preoperative | 135.8 ± 6.1 | 136.2 ± 8.2 | .893a |
| Postoperative, 2 years | 145.0 ± 5.8 | 145.0 ± 4.1 | >.999a |
| K-L grade, n | .688c | ||
| Grade 2/3/4 | 4/9/0 | 6/7/0 | |
| HKAA†, ° | |||
| Preoperative, | −6.6 ± 1.4 | −6.7 ± 1.9 | .833a |
| Postoperative, 2 years | 3.0 ± 1.4 | 2.2 ± 1.4 | .155a |
| MPTA, ° | |||
| Preoperative, | 83.6 ± 1.2 | 83.5 ± 1.4 | .840a |
| Postoperative, 2 years | 93.4 ± 2.3 | 92.9 ± 1.6 | .545a |
| Posterior slope, ° | |||
| Preoperative, | 8.7 ± 1.6 | 7.2 ± 2.4 | .090a |
| Postoperative, 2 years | 9.5 ± 2.8 | 9.2 ± 3.2 | .785a |
| Correction angle, ° | 9.9 ± 1.4 | 9.6 ± 1.5 | .601a |
| Baseline Intraoperative ICRS grade, n | |||
| MFC, 3/ 4 | 3/ 10 | 4/ 9 | >.999c |
| MTP, 2/ 3/ 4 | 1/ 7/ 5 | 1/ 4/ 8 | .695c |
Values are present as mean ± SD.
Student t-test.
Mann-Whitney U test.
Pearson chi-square test.
Fisher’s exact test.
Statistical significance was set at <.05.
Abbreviations: ADMSC, adipose-derived mesenchymal stem cell; BMI, body mass index; DM, diabetes mellitus; FC, flexion contracture; FF, further flexion; HKAA, hip-knee-ankle angle; HTN, hypertension; MFC, medial femoral condyle; MPTA, medial proximal tibial angle; MTP, medial tibial plateau; ICRS, International Cartilage Repair Society; K-L, Kellgren-Lawrence.