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. 2022 Jun 22;2022(6):CD015060. doi: 10.1002/14651858.CD015060
Outcomes Outcome measure Synthesis
Proteinuria Remission – dichotomous or yes/no as  defined by the study RR or OR, CI, I²
Mild/Moderate/Severe or similar qualitative descriptive scale Summarise
Absolute proteinuria measurements:
  • % change

  • Difference pre and post, time point A versus time point B

  • Continuous data – measurement (g/L or UPCR)

MD
Haematuria  Gross or microscopic  Summarise
Change:
  • Difference pre and post, time point A versus time point B

MD
Kidney function SCr (µmol/L)
  • Pre, post absolute change

  • Rate of change over time

  • Relative change: doubling of SCr ‐ yes/no


eGFR
  • GFR loss ≥ 50% during follow‐up ‐ dichotomous or yes/no

  • Absolute change (pre, post)

  • Rate of change


Kidney failure
  • Dialysis, kidney transplant – yes/no

  • Kidney survival

RR or OR, CI, I²
Time to event
 
 
 
 
Infection
 
Dichotomous or yes/no
 
RR or OR, CI, I²
Descriptive
Malignancy
 
Dichotomous or yes/no
 
RR or OR, CI, I²
Descriptive
Diabetes or 
impaired blood glucose
Dichotomous or yes/no
 
RR or OR, CI, I²
Descriptive
Hypertension  Dichotomous or yes/no
 
RR or OR, CI, I²
Descriptive
Hospitalisation Number of hospitalised days
 
RR or OR, CI, I²
 
Death
 
Death (any cause) ‐ dichotomous or yes/no
 
RR or OR, CI, I²
 
Patient‐oriented outcomes Missed school days – number of days
Reduced quality of life ‐ scale
MD
RR, CI, I²
Descriptive
Adverse events Dropout rate due to treatment related adverse events
Bone density, fracture or short stature
Descriptive