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. 2022 Jun 22;2022(6):CD000190. doi: 10.1002/14651858.CD000190.pub4

AbuRahma 2010.

Study characteristics
Methods Method of randomisation: unknown
Concealment: sealed envelopes that were opened just before surgery
Blinding: not reported
Cross‐overs: none (ITT analysis)
Exclusions during trial: none
Loss to follow‐up: none
Participants USA
200 participants, 200 operations
Routine shunting: 98 operations
Selective shunting: 102 operations
Age: 45 to 89 years, mean 68 years
Gender: 48% male, 52% female
Comparability: age, gender, vascular risk factors similar between 2 groups
More asymptomatic ipsilateral arteries in routine shunting group: 58% versus 53%
Contralateral artery stenosis (mean %) routine shunting group: 38%; selective shunting group: 40%
Interventions Treatment: selective shunting group; shunt selected if systolic stump pressure < 40 mmHg
Control: routine shunting group
All operations under general anaesthetic; unknown patching rate
Outcomes TIA, stroke, combined stroke/TIA, death, bleeding, myocardial infarction, congestive heart failure, asymptomatic carotid thrombosis, recurrent laryngeal injury, all complications, number of shunted arteries
Notes Exclusion: none
Follow‐up: 30 days
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Quote: "200 CEA patients were randomised into"
However, the randomised method was unknown.
Allocation concealment (selection bias) Low risk Quote: "Randomization was done using sealed envelopes that were open just before surgery".
Blinding of participants and personnel (performance bias)
All outcomes Unclear risk Not reported
Blinding of outcome assessment (detection bias)
All outcomes Unclear risk Not reported
Incomplete outcome data (attrition bias)
All outcomes Low risk No loss to follow‐up in either group
Selective reporting (reporting bias) Unclear risk Study authors did not report prespecified outcome.
Other bias Low risk No other potential biases