Figure 2.
Atypical pleomorphic lipomatous tumor comprised of spindle cells, adipocytic cells, pleomorphic giant cells, and scattered lipoblasts embedded in a myxoid and collagenous extracellular matrix (A, hematoxylin-eosin (HE), 200x; B, HE, x400) with occasional hyperchromatic nuclei (B, inset). The tumor cells express CD34 (C, x400), lack MDM2 expression (C, inset, x400), and show RB1 loss (D, x400).