Table 1.
Autoimmune disorders associated with thymomas
| Neuromuscular | Myasthenia gravis |
| Myotonic dystrophy | |
| Limbic encephalitis | |
| Peripheral neuropathy Autonomic neuropathy | |
| Acquired neuromyotonia Morvan syndrome (neuromyotonia and encephalitis) | |
| Stiff person syndrome Cerebelar degeneration Polymyositis (carcinomas) | |
| Hematologic disorders | Red cell aplasia |
| Pernicious anemia | |
| Erythrocytosis | |
| Pancytopoenia | |
| Hemolytic anemia | |
| Leukemia | |
| Multiple myeloma | |
| Collagen and autoimmune disorders | Systemic lupus erythematosus |
| Rheumatoid arthritis | |
| Sjogren syndrome | |
| Scleroderma | |
| Interstitial pneumonitis | |
| Immune deficiency disorders | Hypogammaglobulinemia (Good syndrome) |
| T-cell-deficiency syndrome | |
| Endocrine disorders | Multiple endocrine neoplasia |
| Cushing syndrome | |
| Thyroiditis | |
| Dermatologic disorders | Pemphigus |
| Lichen planus | |
| Chronic mucosal candidiasis | |
| Alopecia areata | |
| Miscellaneous | Giant cell myocarditis |
| Nephrotic syndrome | |
| Ulcerative colitis | |
| Hypertrophic osteoarthropathy |
Bernard C, Frih H, Pasquet F, et al. Thymoma associated with autoimmune diseases: 85 cases and literature review. Autoimmun Rev 2016; 15:82–92.
Bouchet ME, Dansin E, Kerjouan M, et al. B004. OS01.04. Prevalence of autoimmune diseases in thymic epithelial tumors insights from RYTHMIC. Mediastinum 2017:4 doi: 10.21037/med.2017.AB004
Padda SK, Yao X, Antonicelli A, et al. Paraneoplastic syndromes and thymic malignancies: an examination of the International Thymic Malignancy Interest Group Retrospective Database. J Thorac Oncol 2018; 13:436–46.
Sources: Girard N, Ruffini E, Marx A, Faivre-Finn C, Peters S; ESMO Guidelines Committee. Thymic epithelial tumours: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol 2015; 26(Suppl. 5):v40–55.