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. Author manuscript; available in PMC: 2022 Jun 22.
Published in final edited form as: Nat Cardiovasc Res. 2021 Dec 23;1(1):28–44. doi: 10.1038/s44161-021-00002-8

Fig. 7 |. CVD induces inflammatory bone marrow endothelial cell gene expression.

Fig. 7 |

a, Experimental outline. WD, western diet. bd, Differential gene expression in bone marrow endothelial cells assessed by RNA-seq (n = 3 mice per group). eg, GSEA plots of gene sets related to inflammation. NES, normalized enrichment score; FDR, false discovery rate; GO, gene ontology; IFN-γ; interferon-γ; KEGG, Kyoto Encyclopedia of Genes and Genomes; LPS, lipopolysaccharide. h, Plot of gene set enrichment in Apoe−/− mice compared to controls. Neg., negative; posit., positive; reg., regulation; TLR, Toll-like receptor.