Table 1.
Baseline demographic and clinical characteristics by sequence: Group A Relaxation on site-MBFP, Group B MBFP – relaxation on site (N = 47).
| Factors | Group A (N = 23) |
Group B (N = 22) |
p-value |
|---|---|---|---|
| N(%)/Mean ± SD)/Median(IQR) | N(%)/Mean ± SD)/Median(IQR) | ||
| Age (year) | 22(21–39) | 24.5(20–50) | .923m |
| Occupation | .566f | ||
| Register nurse (2) | 14(56.0) | 11(50.0) | |
| Nursing assistant (0) | 1(4.0) | 3(13.6) | |
| University student(1) | 10(40.0) | 8(36.4) | |
| Education | .349f | ||
| Master (3) | 1(4.0) | 3(13.6) | |
| Bachelor (2) | 9(36.0) | 5(22.7) | |
| University student (1) | 14(56.0) | 11(50.0) | |
| High school (0) | 1(4.0) | 3(13.6) | |
| Married (1) | 3(12.0) | 8(36.4) | .057f |
| Neuropsychological test | |||
| MOCA | 26.72 ± 1.74 | 26.36 ± 1.56 | .467t |
| VAS-A (anxiety) | 65.05 ± 12.76 | 63.70 ± 12.20 | .713t |
| PHQ-9 (depression) | 4(2–6) | 4(3–6) | .433m |
| PSQI (sleep quality) | 7(4–8) | 7(5–9) | .555m |
| Digit span Forward | 8.40 ± 1.29 | 7.36 ± 2.36 | .076t |
| Digit span Backward | 4(3–4) | 3.5(3–4) | .924m |
| Biomarkers | |||
| Morning serum glucose (mg/dl) | 86.0(83.0–89.0) | 86.5(84.0–94.0) | .522m |
| Morning serum cortisol (μg/dl) | 8.64(8.16–12.11) | 7.86(5.83–11.30) | .077*m |
| Serum BDNF (ng/ml) | 6.97(4.09–9.45) | 5.74(2.27–9.90) | .765m |
| Oxphos complex I | 0.96(0.79–1.17) | 1.13(0.87–1.45) | .388m |
| Oxphos complex II | 2.03(1.93–2.40) | 1.99(1.61–2.47) | .429m |
| Oxphos complex III | 1.16(1.06–1.48) | 1.11(1.06–1.34) | .258m |
| Oxphos complex IV | 1.43(1.11–2.29) | 1.39(1.14–1.72) | .790m |
| Oxphos complex V | 1.14(1.05–1.64) | 1.40(1.05–1.54) | .974m |
| Heart Rate Variability (HRV) | |||
| Low frequency (LF) | 25.43 ± 11.95 | 20.12 ± 6.55 | .062t |
| High frequency (HF) | 16.50(8.85–22.03) | 13.71(10.85–18.51) | .773m |
| LF/HF ratio | 1.69 ± 0.53 | 1.38 ± 0.42 | .034*t |
| SDNN | 56.84 ± 16.10 | 52.54 ± 15.32 | .356t |
| RMSSD | 31(21–40) | 27.5(24–38) | .957m |
t = t-test, m = mann-whitney test, f = fisher's exact test.
*p-value ≤ 0.05: statistically significant with null hypothesis the difference of mean equal 0.
** p-value ≤ 0.05: statistically significant with null hypothesis the mean of fatigue group is more than non-fatigue.
mean fatigue score of total 9 ± SD = 3.83 ± 0.92 in fatigue groups, 1.21 ± 0LLL.73 in non-fatigue groups.