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. 2022 Apr 29;11:100137. doi: 10.1016/j.cpnec.2022.100137

Table 2.

The sensitivity analysis from the result of the baseline and after intervention either relaxation or MBFP in period one of the cross over trial.


Measurement
Group A (relaxation)
Group B (MBFP)
The difference of changing from baseline: Group B – Group A
Baseline
Mean (SD)
After Mean (SD) Correlation
R (95% CI)
Baseline
Mean (SD)
After Mean (SD) Correlation
R (95% CI)
Mean difference (SE) P value
Serum BDNF:ng/ml 6.95 (3.58) 7.59 (3.93) 0.69 (0.38–0.86) 6.73 (3.09) 7.25 (2.74) 0.60 (0.22–0.81) 0.88 (0.77) 0.26
Cortisol: mg/dl 12.4 (8.54) 13.43(11.32) 0.12 (−0.14 to0.52) 13.12 (9.10) 13.67 (9.45) 0.15 (−0.23 to 0.65) 0.07 (1.56) 0.96
Oxphos I 1.02 (0.28) 0.85 (0.25) −0.69 (-0.23 to −0.89) 1.51 (0.89) 1.26 (0.65) −0.39 (−0.03 to0.69) - 0.70 (0.46) 0.15
Oxphos II 1.93 (0.38) 1.96 (0.41) 0.71
0.26 to 0.90)
2.78 (1.70) 2.11 (2.08) - 0.11 (-0.32 to 0.50) −0.08 (0.24) 0.76
Oxphos III 1.11 (0.28) 1.08 (0.20) 0.13 (0.43–0.62) 1.53(0.76) 1.33(0.46) −0.17 (-0.26 to 0.54) −0.17 (0.24) 0.48
Oxphos IV 1.32(0.41) 1.29 (0.20) −0.68 (−0.19 to 0.88) 1.89(1.02) 1.54(0.77) −0.32 (-0.12 to 0.64) −0.26 (0.35) 0.40
Oxphos V 1.00 (0.41) 0.82 (0.22) 0.68 (0.19–0.88) 1.37(0.66) 1.36 (0.64) 0.39 (0.03–0.69) 0.168 (0.22) 0.45
Clinical outcomes
VAS-A 0–100 71.5(15.6) 56.3(12.35) −0.13 (−0.56 to-0.01) 64.7(13.5) 32.5(11.45) −0.54 (−0.75 to 0.12) −13.76(4.72) 0.01
Forward digit span 7.86 (1.17) 12.50(1.50) −0.37 (−0.06 to −0.67) 8.06(2.29) 12.72(1.74) 0.43 (0.04–0.73) −0.24 (0.64) 0.87
Backward digit span 3.68 (0.89) 7.05 (0.65) 0.11 (−0.32 to 0.49) 3.50(0.71) 6.89(0.58) 0.29 (-0.20 to 0.65) 0.02 (0.29) 0.93
Heart rate variability
LF/HF ratio 1.51(0.51) 1.66(0.51) 0.51 (0.11–0.76) 1.55(0.57) 1.58(0.37) 0.24
-(0.25 to 0.62)
−0.12 (0.17) 0.47
SDNN 50.50(16.20) 48.41(18.79) 0.69 (0.37–0.86) 52.94(12.46) 48.28(21.45) 0.47 (0.01–0.76) 0.86 (4.97) 0.86
RMSSD 27.77(10.84) 25.68(12.45) 0.38 (−0.04 to 0.68) 28.00(9.99) 24.78(11.58) 0.27 (−0.22 to 0.64) −3.02 (3.42) 0.38

*p-value0.05: statistically significant with null hypothesis the difference of mean equal 0 ** p-value0.05: statistically significant with null hypothesis the mean of fatigue group is more than non-fatigue mean fatigue score of total 9 ± SD = 3.83 ± 0.92 in fatigue groups, 1.21 ± 0.73 in non-fatigue groups.