Table 1.
Cancer clinical trials investigating fecal microbiota transplantation (FMT) therapy
Trial no. | Phase | Cancer type | Intervention | Sponsor/investigator |
---|---|---|---|---|
NCT03341143 | II | Melanoma | FMT (via colonoscopy) + immune checkpoint inhibitors | UPMC Hillman Cancer Center |
NCT03353402 | I | Melanoma | FMT (via colonoscopy and stool capsules) + immune checkpoint inhibitors | Sheba Medical Center |
NCT03772899 | I | Melanoma | FMT + immune checkpoint inhibitors | Lawson Health Research Institute |
NCT04577729 | – | Melanoma | Autologous or allogeneic FMT + immune checkpoint inhibitors | Medical University of Graz |
NCT04521075 | I/II | Melanoma NSCLC |
FMT (stool capsules) + immune checkpoint inhibitors | Sheba Medical Center |
NCT04056026 | I | Mesothelioma | FMT (via colonoscopy) + immune checkpoint inhibitors | ProgenaBiome |
NCT04116775 | II | Prostate | FMT (via endoscopy) + immune checkpoint inhibitors + enzalutamide | VA Portland Health Care System |
NCT04130763 | I | Gastrointestinal | FMT (stool capsules) + immune checkpoint inhibitors | Peking University |
NSCLC, non-small cell lung cancer.