Table 2.
Clinical trials investigating bacterial isolates
| Trial no. | Phase | Cancer type | Intervention | Sponsor/investigator |
|---|---|---|---|---|
| NCT03775850 | I/II | Solid tumors | EDP1503 (bifidobacterium capsule) + pembrolizumab | Evelo Biosciences |
| NCT03595683 | II | Melanoma | EDP1503 (bifidobacterium capsule) + pembrolizumab | Evelo Biosciences |
| NCT03829111 | I | Renal cell carcinoma | CBM588 (Clostridium butyricum probiotic) + nivolumab and ipilimumab | City of Hope Medical Center |
| NCT03637803 | I/II | Solid tumors | MRx0518 (Enterococcus gallinarum capsule) + immune checkpoint inhibitors | 4D Pharma |