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. 2021 Mar 17;6:100048. doi: 10.1016/j.cpnec.2021.100048

Table 1.

Gene expression Fold Up and Down-regulation (vs. 4 ​h Control group).

Symbol 4 ​h
12 ​h
LPS PA LPS/PA Ctl LPS PA LPS/PA
CCL2 2.09 −1.25 1.07 −3.67 −1.41 −2.83 −1.25
CCL22 1.90 1.62 1.51 2.51 1.87 2.37 3.17
CCL24 −1.78 −1.85 −1.02 2.76 2.05 2.61 2.41
CCL3 1.37 1.39 1.21 2.72 2.02 2.57 2.95
CCR1 1.43 −1.26 1.90 2.49 1.85 2.59 2.17
CCR2 1.87 2.22 2.21 2.36 2.16 1.80 22.82
CXCL1 3.08 −1.66 2.49 −1.79 2.08 −1.59 6.89
CXCL10 2.06 −1.66 1.63 1.27 1.09 1.20 3.88
CXCL2 2.52 −1.66 2.26 −1.93 1.81 1.02 5.98
IL15 −1.05 1.42 1.46 3.57 2.20 3.74 3.42
IL6 1.63 1.45 2.38 −1.51 −1.17 3.80 7.49
CXCL8 1.89 −2.00 1.82 −2.73 1.17 −1.48 4.42
TNFSF14 0.55 1.08 1.37 4.21 3.13 3.98 3.68
C3 −1.72 −1.87 −2.37 −2.25 −1.92 −1.48 −2.58
CCL2 2.09 −1.25 1.07 −3.67 −1.41 −2.83 −1.25
CCL11 1.18 −1.24 1.02 −1.79 −1.19 −3.46 −2.32
CCL5 −1.55 −1.50 1.09 −4.18 −4.76 −4.42 −4.79
CD14 −1.49 −2.59 −1.77 −2.54 −2.56 −1.87 −1.36
CRP −1.16 −4.34 −1.52 −1.23 −1.03 1.28 1.67
CXCL6 −1.18 −2.26 −2.21 −1.11 −1.74 1.02 2.45
IL10RB 1.09 1.14 1.09 −2.06 −3.58 −3.01 −4.39
IL17A −1.38 −2.73 −1.45 −1.23 −2.19 −1.25 1.17
TLR4 −1.27 1.17 1.08 −1.47 −2.22 −1.21 1.05
TLR5 −4.44 −2.56 −1.77 −1.84 −2.48 −1.95 −2.11
TLR7 −1.14 1.49 1.26 −1.87 −3.35 −2.14 −2.27
GAPDH −1.07 −1.33 −1.17 −1.89 −1.03 −1.02 −1.21

HMC3 were treated with 100 ​ng/ml of LPS, 200 ​μM of PA or LPS plus PA for 4 and 12 ​h. RNA was isolated and subjected to PCR array as described in the Methods. Bold numbers indicated fold changes (>2.0 or ​< ​-2.0) of gene expression compare with 4 ​h control group.