Table 2.
Mutations per Polycomb repressive complex 2 (PRC2) gene in tumor samples of patients treated with immune checkpoint inhibitors (discovery cohort)
PRC2 gene | Missense | Truncating | Inframe | Splice | Structural variant/fusion |
---|---|---|---|---|---|
EZH2 (2.4%) | 29 | 6 | 2 | 3 | 0 |
EZH1 (1.2%) | 4 | 0 | 0 | 0 | 1 |
SUZ12 (0.9%) | 14 | 2 | 0 | 0 | 0 |
EED (0.7%) | 9 | 2 | 1 | 0 | 1 |