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. 2022 Apr 12;40(6):605–617. doi: 10.1093/stmcls/sxac025

Figure 1.

Figure 1.

Overexpression of Fgf10 promotes de novo alveologenesis after hyperoxia injury in newborn pups. (A) C57BL6 mice are subjected to hyperoxia from P2 to P9 and subsequently exposed to normoxia from P9 through P45. The lungs were harvested at P9, P15, and P45 to carry out morphometry analysis between 2 HYX and NOX. P < .05 is considered significant. Scale bar for low magnification: 500 μm and for high magnification: 50 μm. (B) Transgenic Rosa26rtTA/+; Tg(tet(O)Fgf10)/+ mice exposed to HYX from P2 to P9 were exposed to DOX food from P9 to P42 at 3 intervals. Morphometry analysis was done at P9, P15, and P45. Scale bar for low magnification: 500 μm and for high magnification: 50 μm.