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. 2022 Jun 22;8(25):eabn5683. doi: 10.1126/sciadv.abn5683

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Fig. 2. — (A) Transcriptomic subtypes and their histopathological features. Heatmaps were organized by M cluster grouping for molecular subtypes, histopathology, and mRNA signatures of biological processes, mRNA signatures of metabolism, and cell types by MCP-counter. Tumors are in columns, grouped by the M cluster membership. (B) Proteomic subtypes of mouse liver tumors. Heatmap depicts relative abundance (Z score) of signature proteins (row) in tumors (column). Classification of tumors using the M proteomic signatures and human HCC proteomic signatures is indicated on top. Biological functions of signature proteins were analyzed by enrichment of MsigDB ontologies.