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. 2022 Jun 8;9:876607. doi: 10.3389/fmolb.2022.876607

TABLE 2.

Independent prognostic factors for DFS in TCGA dataset.

Characteristics Total (N) Univariate analysis Multivariate analysis
Hazard ratio (95% CI) p value Hazard ratio (95% CI) p value
Risk score 69 35.806 (6.384–200.838) <0.001 a 28.492 (3.902–208.069) <0.001 a
Age (years) 69
 <65 31 Reference
 ≥65 38 1.025 (0.447–2.349) 0.954
Sex 69
 Male 37 Reference
 Female 32 2.372 (1.001–5.623) 0.050 2.055 (0.834–5.062) 0.118
N 66
 N0 23 Reference
 N+ 43 3.881 (1.301–11.576) 0.015 a 1.160 (0.360–3.744) 0.803
T 68
 T1+T2 17 Reference
 T3+T4 51 2.379 (0.789–7.174) 0.124
Stage 68
 Stage I 12 Reference
 Stage IIA 12 1.440 (0.197–10.498) 0.719
 Stage IIB 43 4.474 (1.010–19.821) 0.049 a
 Stage III+IV 1 0.000 (0.000-Inf) 0.998
Grade 68
 G1+G2 51 Reference
 G3+G4 17 1.446 (0.593–3.521) 0.417
Alcohol drinking history 64
 No 25 Reference
 Yes 39 1.116 (0.461–2.701) 0.808
Site 69
 Body + tail + others 20 Reference
 Head 49 3.799 (1.259–11.463) 0.018 a 2.381 (0.799–7.095) 0.119
Tumor diameter 61 0.896 (0.643–1.249) 0.517
Chemotherapy 69
 No 19 Reference
 Yes 50 2.111 (0.625–7.131) 0.229
a

p-value is less than 0.05.