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. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: Brain Behav Immun. 2021 Aug 14;98:245–250. doi: 10.1016/j.bbi.2021.08.218

Figure 3. Inoculation with Parabacteroides distasonis induces depressive-like behavior in SAMP1 mice.

Figure 3.

(a) Administration of P. distasonis did increase time immobile during tail suspension (b) but did not worsen ileitis. Alluvial plot of 16s rRNA data for (c) sham and (d) P. distasonis gavaged groups reveals largely similar microbiomes. (e) Relative abundance of Parabacteroides in sham versus inoculated group. Tail suspension was analyzed using student’s t-test, histology was analyzed with Mann-Whitney test, and relative abundance was measured using Wilcoxon Rank Sum test. Symbols represent individual mice (n=10) from two technical replicates, bars indicate mean ± S.E.M. (n.s. p > 0.05, *p < 0.05, **p < 0.01, ***p< 0.001 and ****p < 0.0001).