Table 3.
Dialysate sodium—association with SBP BP decline and IDH
| Difference in SBP decline (95% CI) | Risk of IDH (SBP decline ≥20 mmHg) | |||
|---|---|---|---|---|
| for higher versus lower DNa | for higher versus lower DNab | |||
| Absolute change | Relative change | Odds ratio | Prevalence ratio | |
| (mmHg) | (%) | (95% CI) | (95% CI) | |
| Unadjusted | −1.5 (−6.6 to 3.6) | −2.0 (−5.3 to 1.4) | 0.72 (0.36 to 1.44) | 0.92 (0.68 to 1.24) |
| Model 1 | −1.8 (−6.9 to 3.2) | −2.1 (−5.5 to 1.3) | 0.71 (0.36 to 1.43) | 0.92 (0.68 to 1.23) |
| Model 2 | −3.2 (−7.9 to 1.5) | N/Aa | 0.58 (0.25 to 1.36) | 0.92 (0.68 to 1.23) |
| Model 3 | −4.4 (−9.1 to 0.3) | −2.9 (−6.3 to 0.6) | 0.48 (0.20 to 1.14) | 0.86 (0.64 to 1.17) |
| Model 4 | −7.7 (−13.4 to −1.9) | −4.7 (−8.6 to −0.8) | 0.37 (0.15 to 0.94) | 0.73 (0.48 to 1.12) |
Model 1 adjusted for baseline heart failure; Model 2 adjusted for heart failure and pre-HD systolic BP; Model 3 adjusted for heart failure, pre-HD systolic BP and sex; Model 4 adjusted for heart failure, pre-HD systolic BP, sex and pre-HD weight.
a
Pre-HD systolic BP was not included in the models for relative change due to collinearity.
b
Odds ratios were estimated using mixed-effects logistic regression and prevalence ratios with mixed-effects Poisson regression.