Table 3.
Genotype distribution among group and p values.
| Gene | rs | Genotype distribution and allele distributions, n (%) | p valueGenotype | p valueAllele | p valueRecessive | ||
|---|---|---|---|---|---|---|---|
| Genotype | Orthognathic mandible | Mandibular retrognathism | |||||
| TGFB1 | rs1800469 | TT | 5 (10.0) | 4 (4.4) | 0.310 | 0.525 | 0.199 |
| CT | 18 (36.0) | 41 (45.6) | |||||
| CC | 27 (54.0) | 45 (50.0) | |||||
| A | 28 (28.0) | 49 (27.2) | |||||
| G | 72 (72.0) | 131 (72.8) | |||||
| rs4803455 | CC | 10 (20.8) | 18 (21.4) | 0.740 | 0.692 | 0.478 | |
| CA | 27 (56.3) | 42 (50.0) | |||||
| AA | 11 (22.9) | 24 (28.6) | |||||
| C | 47 (48.0) | 78 (46.4) | |||||
| A | 49 (52.0) | 90 (57.3) | |||||
|
| |||||||
| TGFBR2 | rs3087465 | AA | 6 (12.0) | 3 (3.3) | 0.098 | 0.603 | 0.045∗ |
| AG | 21 (42.0) | 48 (53.3) | |||||
| GG | 23 (46.0) | 39 (43.3) | |||||
| A | 33 (33.0) | 54 (30.0) | |||||
| G | 67 (67.0) | 126 (70.0) | |||||
| rs764522 | GG | 0 (0.0) | 2 (2.3) | 0.575 | 0.525 | 0.302 | |
| GC | 11 (23.9) | 22 (25.0) | |||||
| CC | 35 (76.1) | 64 (72.7) | |||||
| G | 11 (12.0) | 26 (14.8) | |||||
| C | 81 (88.0) | 150 (85.2) | |||||
Note: ∗means statistically significant difference; n: number of individuals; %: percent; rs: the code of polymorphisms; TGFB1: transforming growth factor beta 1; TGFBR2: transforming growth factor beta receptor 2; C: cytosine; A: adenine; T: thymine; G: guanine.