Table 2.
Correlations between the syntenin expression level and the clinicopathological features of GC patients.
| Variables | Syntenin expression | Total | χ 2 | p value | |
|---|---|---|---|---|---|
| High | Low | ||||
| Age (years) | |||||
| ≤65 | 44 | 43 | 87 | 4.170 | 0.041∗ |
| >65 | 33 | 15 | 48 | ||
| Sex | |||||
| Female | 21 | 15 | 36 | 0.034 | 0.854 |
| Male | 56 | 43 | 99 | ||
| Borrmann type | |||||
| I + II | 41 | 37 | 78 | 1.508 | 0.219 |
| III + IV | 36 | 21 | 57 | ||
| Lauren type | |||||
| Intestinal GC | 41 | 30 | 71 | 2.319 | 0.314 |
| Diffuse GC | 27 | 16 | 43 | ||
| Mixed GC | 9 | 12 | 21 | ||
| Grade of differentiation | |||||
| Well + moderate | 42 | 31 | 73 | 0.016 | 0.899 |
| Poor + not | 35 | 27 | 62 | ||
| T stage | |||||
| T1 | 0 | 2 | 2 | 3.419 | 0.064 |
| T2 + T3 + T4 | 77 | 56 | 133 | ||
| N stage | |||||
| N0 | 8 | 3 | 11 | 0.607 | 0.436 |
| N1 + N2 + N3 | 69 | 55 | 124 | ||
| M stage | |||||
| M0 | 66 | 56 | 122 | 4.465 | 0.035∗ |
| M1 | 11 | 2 | 13 | ||
| TNM stage | |||||
| I + II | 5 | 12 | 17 | 6.057 | 0.014∗ |
| III + IV | 72 | 46 | 118 | ||
| CEA (ng/ml) | |||||
| ≤5 | 56 | 43 | 99 | 0.034 | 0.854 |
| >5 | 21 | 15 | 36 | ||
| HER2 | |||||
| Negative | 65 | 51 | 116 | 0.338 | 0.561 |
| Positive | 12 | 7 | 19 | ||
| PD-L1 | |||||
| Negative | 42 | 40 | 82 | 2.885 | 0.089 |
| Positive | 35 | 18 | 53 | ||
∗ Statistically significant (p < 0.05).