Figure 2.

Identification of osteoporosis-associated mRNAs. (a) The soft thresholding power β was selected as 15 (sale free R² = 0.9) to ensure a scale-free network. (b) Hierarchical clustering tree and the module colors were plotted to display the modules. (c) Nine modules were obtained with Pearson's correlation coefficients and P values. (d) The differentially expressed genes were screened out in 17 osteoporosis and 19 healthy samples with the cutoff criteria adjusted P value < 0.01 and |log2FC| ≥ 1. (e) Venn diagram displayed the shared miRNAs between 1,572 differentially expressed genes and 3,344 genes in the turquoise module.