Figure 3.

Folate receptor 4 (FR4) expression as predictor of overall survival in esophageal squamous cell carcinoma (ESCC) patients underwent adjuvant chemotherapy. The Kaplan-Meier estimate was used to perform the survival analysis from the date of the initial diagnosis and the log-rank test was used to compare the subgroup survival. (a and b) Overall survival (OS) and disease-free survival (DFS) in patients with or without FR4 expression. (c and d) OS and DFS in patients who underwent adjuvant chemotherapy with or without FR4 expression. FR positive (n = 100) and FR negative (n = 48).