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Effect of Cav2.2 on clinical score and sciatic nerve tissue of rats. (a) Clinical score record of rats during 18 days of immunization; (b) changes in body weight of rats during 18 days of immunization; (c) luxol fast blue (LFB) staining-based observation of the degree of cell infiltration and demyelination in sciatic nerve tissue of rats on the 18th day of immunization. ∗∗P < 0.01 vs. control group, ##P < 0.01 vs. EAN-shRNA group.
