Table 1.
Primary histopathological diagnoses of adult kidney biopsies in Flanders
| Primary histopathological diagnosis | N | % | Incidence rate (p.m.p./year) |
|---|---|---|---|
| Glomerular | 1119 | 54.5 | 70.4 |
| IgA nephropathy | 357 | 17.4 | 22.5 |
| FSGS | 185 | 9.0 | 11.6 |
| ANCA-associated vasculitis and pauci-immune glomerulonephritis | 150 | 7.3 | 9.4 |
| Membranous nephropathy | 113 | 5.5 | 7.1 |
| Lupus nephritis | 85 | 4.1 | 5.3 |
| MCD | 69 | 3.4 | 4.3 |
| Glomerulopathy, NOS | 45 | 2.2 | 2.8 |
| Infection-related immune-complex GN | 38 | 1.9 | 2.4 |
| Alport syndrome/thin membrane disease | 29 | 1.4 | 1.8 |
| Anti-GBM nephritis | 11 | 0.5 | 0.7 |
| C3 glomerulopathy | 10 | 0.5 | 0.6 |
| Cryoglobulinemic GN | 8 | 0.4 | 0.5 |
| Monoclonal immunoglobulin-associated glomerulopathy | 8 | 0.4 | 0.5 |
| FSGS/MCD | 7 | 0.3 | 0.4 |
| Nonamyloid deposition glomerulopathy | 4 | 0.2 | 0.3 |
| Tubulointerstitial | 376 | 18.3 | 23.7 |
| Tubulointerstitial nephritis | 187 | 9.1 | 11.8 |
| ATN | 137 | 6.7 | 8.6 |
| Tubulointerstitial pathology, NOS | 18 | 0.9 | 1.1 |
| Monoclonal immunoglobulin-associated tubular disease | 17 | 0.8 | 1.1 |
| Crystal/cylinder deposition | 16 | 0.8 | 1.0 |
| Chronic pyelonephritis | 1 | <0.1 | 0.1 |
| Vascular | 173 | 8.4 | 10.9 |
| Nephrosclerosis | 119 | 5.8 | 7.5 |
| Thrombotic microangiopathy | 48 | 2.3 | 3.0 |
| Cholesterol emboli | 4 | 0.2 | 0.3 |
| Vasculitis without glomerulonephritis | 1 | <0.1 | 0.1 |
| Kidney infarction | 1 | <0.1 | 0.1 |
| All/any compartment(s) | 248 | 12.1 | 15.6 |
| Diabetic kidney disease | 138 | 6.7 | 8.7 |
| Amyloidosis | 69 | 3.4 | 4.3 |
| Nonamyloid monoclonal deposition disease | 17 | 0.8 | 1.1 |
| End-stage kidney disease | 7 | 0.3 | 0.4 |
| Medication-induced nephropathy | 7 | 0.3 | 0.4 |
| Idiopathic nodular glomerulosclerosis | 5 | 0.2 | 0.3 |
| Congenital/hereditary syndromes | 4 | 0.2 | 0.3 |
| Storage disease | 1 | <0.1 | 0.1 |
| No kidney disease/no diagnosis/tumour | 138 | 6.7 | 8.7 |
| No diagnosis | 101 | 4.9 | 6.4 |
| Normal | 33 | 1.6 | 2.1 |
| Tumour | 4 | 0.2 | 0.3 |
| Total | 2054 | 100.0 | 129.3 |
The primary histopathological diagnoses (FCGG level 1) are categorized per kidney tissue compartment (FCGG level 2). The bold values are the 4 main categories and bold numbers represent the sums of the values of the different subcategories listed below.
Anti-GBM nephritis: anti-glomerular basement membrane nephritis; FSGS/MCD: focal segmental glomerulosclerosis or minimal change disease, subdivision not possible; NOS: not otherwise specified; GN: glomerulonephritis.