Table 2.
Final clinical diagnoses of adult kidney biopsies in Flanders
| Final clinical diagnosis | N | % | Incidence rate (p.m.p./year) |
|---|---|---|---|
| Glomerular | 1152 | 56.1 | 72.5 |
| IgA nephropathy | 355 | 17.3 | 22.3 |
| FSGS | 192 | 9.3 | 12.1 |
| ANCA-associated vasculitis and pauci-immune glomerulonephritis | 148 | 7.2 | 9.3 |
| Membranous nephropathy | 113 | 5.5 | 7.1 |
| MCD | 96 | 4.7 | 6.0 |
| Lupus nephritis | 87 | 4.2 | 5.5 |
| Glomerulopathy, NOS | 76 | 3.7 | 4.8 |
| Alport syndrome/thin membrane disease | 25 | 1.2 | 1.6 |
| Membranoproliferative GN | 15 | 0.7 | 0.9 |
| Infection-related immune-complex GN | 13 | 0.6 | 0.8 |
| Anti-GBM nephritis | 10 | 0.5 | 0.6 |
| Cryoglobulinemia | 8 | 0.4 | 0.5 |
| Nephrotic syndrome, no histology | 6 | 0.3 | 0.4 |
| Immunotactoid/fibrillary nephropathy | 6 | 0.3 | 0.4 |
| Hematuria and proteinuria, no histology | 2 | 0.1 | 0.1 |
| Tubulointerstitial | 293 | 14.3 | 18.4 |
| Tubulointerstitial nephritis | 220 | 10.7 | 13.8 |
| ATN | 33 | 1.6 | 2.1 |
| Monoclonal immunoglobulin-associated tubular disease | 20 | 1.0 | 1.3 |
| Crystal/cylinder deposition | 15 | 0.7 | 0.9 |
| Medication-induced nephropathy | 3 | 0.1 | 0.2 |
| Acute pyelonephritis | 2 | 0.1 | 0.1 |
| Vascular | 186 | 9.1 | 11.7 |
| Nephrosclerosis | 127 | 6.2 | 8.0 |
| Thrombotic microangiopathy | 42 | 2.0 | 2.6 |
| Non-AAV vasculitis | 11 | 0.5 | 0.7 |
| Cholesterol emboli | 4 | 0.2 | 0.3 |
| Vascular, NOS | 1 | <0.1 | 0.1 |
| Sickle cell nephropathy | 1 | <0.1 | 0.1 |
| All/any compartment(s) | 408 | 19.9 | 25.7 |
| Diabetic kidney disease | 154 | 7.5 | 9.7 |
| AKI/CKD, NOS | 129 | 6.3 | 8.1 |
| Amyloidosis | 69 | 3.4 | 4.3 |
| Nonamyloid monoclonal deposition disease | 22 | 1.1 | 1.4 |
| Medication-induced nephropathy | 17 | 0.8 | 1.1 |
| Isolated proteinuria or hematuria, no histology | 11 | 0.5 | 0.7 |
| Congenital/hereditary syndromes | 5 | 0.2 | 0.3 |
| Iatrogenic | 1 | <0.1 | 0.1 |
| No kidney disease/tumour | 11 | 0.5 | 0.7 |
| Normal | 7 | 0.3 | 0.4 |
| Tumour | 4 | 0.2 | 0.3 |
| Postrenal | 4 | 0.2 | 0.3 |
| Retroperitoneal fibrosis | 2 | 0.1 | 0.1 |
| Acquired obstructive uropathy/nephropathy | 2 | 0.1 | 0.1 |
| Total | 2054 | 100.0 | 129.3 |
The final clinical diagnoses (ERA level 1) are categorized per kidney tissue compartment (ERA level 2). The bold values are the 4 main categories and bold numbers represent the sums of the values of the different subcategories listed below.
non-AAV vasculitis: non-ANCA-associated vasculitis; AKI/CKD, NOS: non-specific diagnoses of acute kidney injury or chronic kidney disease; Anti-GBM nephritis: anti-glomerular basement membrane nephritis; GN: glomerulonephritis; NOS: not otherwise specified.