Table 2.
Group | Endpoint | Follow-up (median, days) | Events, n | % | Event rates per 100 patient-years | HRb (CKD and HF versus CKD) |
95% CI | P-value |
---|---|---|---|---|---|---|---|---|
CKD and HF | All-cause death | 428 | 3132 | 37.3 | 17.1 | 1.107 | 1.064–1.153 | <.001 |
CKD | 506 | 10 701 | 22.9 | 10.1 | ||||
CKD and HF | Heart failure | 447 | 3994 | 47.6 | 21.7 | 1.439 | 1.387–1.493 | <.001 |
CKD | 541 | 8293 | 17.7 | 7.1 | ||||
CKD and HF | CKD | 545 | 2097 | 25.0 | 10.2 | 1.019 | 0.964–1.078 | .505 |
CKD | 408 | 4114 | 8.8 | 3.6 | ||||
CKD and HF | UACR Progression: <30 to 30–300 mg/g | 504 | 43 | 0.5 | 0.2 | 1.300 | 0.961–1.761 | .089 |
CKD | 551 | 1865 | 4.0 | 1.6 | ||||
CKD and HF | UACR Progression: 30–300 to >300 mg/g | 490 | 1158 | 13.8 | 5.5 | 1.323 | 1.182–1.481 | <.001 |
CKD | 558 | 451 | 1.0 | 0.4 | ||||
CKD and HF | UACR Regression: ≥30 to <30 mg/g | 522 | 85 | 1.0 | 0.4 | 1.147 | 0.854–1.538 | .363 |
CKD | 601 | 109 | 0.2 | 0.1 | ||||
CKD and HF | UACR Regression: ≥300 to <300 mg/g | 493 | 40 | 0.5 | 0.2 | 1.166 | 0.789–1.721 | .441 |
CKD | 552 | 80 | 0.2 | 0.1 | ||||
CKD and HF | Acute kidney failure (ICD-10 code N17) | 592 | 164 | 2.0 | 0.7 | 1.082 | 0.784–1.493 | .633 |
CKD | 532 | 686 | 1.5 | 0.6 |
aAll-cause mortality and first hospitalization for cardiorenal events (HF, CKD, acute kidney failure) or albuminuria transitions during follow-up.
bHR was adjusted according to age, sex, eGFR and the number of associated clinical conditions.