Table 2. Showing the relationship of PD-1 and PD-L1 in tumor cells, and PD-L1 in lymphocytes status with age and percentage of lymphocytes in the tumor. The Mann-Whitney test calculates the statistical significance of difference.

PD-1: Programmed death-1 receptor; PD-L1: Programmed death-ligand 1.

Immunopositivity	Age (years)		Percentage of ymphocytes
	Median (Range)	P-value	Median (Range)	P-value
PD-1 Negative	60 (40-80)	0.83	10 (2-30)	0.04
PD-1 Positive	60 (35-90)		10 (5-25)
PD-L1 in tumor cell Negative	60 (35-90)	0.35	10 (2-30)	0.83
PD-L1 in tumor cell Positive	60 (39-72)		10 (5-20)
PD-L1 in lymphocyte Negative	60 (35-82)	0.81	10 (2-30)	0.40
PD-L1 in lymphocyte Positive	60 (41-90)		10 (5-20)