Table 2. Adsorption, distribution, metabolism, and excretion properties of compounds.
| Number | Compounds | Solubility level | BBB level | CYP2D6 | Hepatotoxicity | Absorption level | PPB level |
| 1 | ZINC000014767731 | 0 | 4 | 1 | 1 | 3 | 0 |
| 2 | ZINC000032840969 | 2 | 4 | 1 | 1 | 3 | 1 |
| 3 | ZINC000043016594 | 1 | 4 | 1 | 0 | 2 | 0 |
| 4 | ZINC000028968107 | 1 | 4 | 0 | 0 | 3 | 0 |
| 5 | ZINC000003831332 | 0 | 4 | 1 | 1 | 3 | 0 |
| 6 | ZINC000014946303 | 0 | 4 | 1 | 0 | 3 | 1 |
| 7 | ZINC000169363256 | 3 | 4 | 1 | 1 | 1 | 1 |
| 8 | ZINC000006003042 | 2 | 4 | 1 | 0 | 1 | 0 |
| 9 | ZINC000040865806 | 3 | 3 | 1 | 1 | 0 | 1 |
| 10 | ZINC000049088142 | 1 | 4 | 1 | 0 | 2 | 1 |
| 11 | ZINC000044086691 | 1 | 4 | 1 | 1 | 3 | 0 |
| 12 | ZINC000013451932 | 3 | 3 | 1 | 0 | 0 | 0 |
| 13 | ZINC000002526389 | 2 | 4 | 0 | 0 | 0 | 0 |
| 14 | ZINC000002528510 | 2 | 4 | 0 | 0 | 0 | 0 |
| 15 | ZINC000027646038 | 3 | 1 | 1 | 1 | 0 | 1 |
| 16 | ZINC000027646060 | 3 | 1 | 1 | 1 | 0 | 1 |
| 17 | ZINC000049878068 | 1 | 4 | 1 | 1 | 3 | 1 |
| 18 | ZINC000011616636 | 2 | 4 | 1 | 1 | 3 | 1 |
| 19 | ZINC000001916008 | 1 | 4 | 1 | 1 | 3 | 0 |
| 20 | ZINC000100772345 | 3 | 4 | 1 | 1 | 1 | 0 |
| 21 | ZINC38433168 | - | - | 1 | 0 | - | 0 |
BBB, blood-brain barrier; CYP2D6, cytochrome P-450 2D6; PPB, plasma protein binding.
Aqueous-solubility level: 0, extremely low; 1, very low, but possible; 2, low; 3, good.
BBB level: 0, very high penetrant; 1, high; 2, medium; 3, low; 4, undefined.
CYP2D6 level: 0, noninhibitor; 1, inhibitor.
Hepatotoxicity: 0, nontoxic; 1, toxic.
Human-intestinal absorption level: 0, good; 1, moderate; 2, poor; 3, very poor.
PPB: 0, absorbent weak; 1, absorbent strong.