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. 2022 Jun 9;14(11):4874–4887. doi: 10.18632/aging.204117

Table 3. Toxicities of compounds.

Number Compounds Mouse NTP Rat NTP Ames DTP
Female Male Female Male
1 ZINC000014767731 0 1 1 0 1 1
2 ZINC000032840969 0 0.961 0 0.692 0.359 0
3 ZINC000043016594 0 1 0.001 0.009 0 1
4 ZINC000028968107 1 0.021 0.06 0.997 1 1
5 ZINC000003831332 1 1 0 0.993 0 1
6 ZINC000014946303 0.991 1 0 1 0 0.007
7 ZINC000169363256 1 1 1 0.176 1 0.01
8 ZINC000006003042 0 1 0 0.001 1 1
9 ZINC000040865806 0 0.065 0.989 0.11 0 0.791
10 ZINC000049088142 0 1 1 0 0 0
11 ZINC000044086691 1 0 0.987 0.998 0.004 1
12 ZINC000013451932 1 0 0 0.685 0 0.999
13 ZINC000002526389 0.999 0.036 0 0.999 0.999 0.769
14 ZINC000002528510 0.999 0.036 0 0.999 0.999 0.769
15 ZINC000027646038 0 0 0 0 0.506 0
16 ZINC000027646060 0 0 0 0 0.482 0
17 ZINC000049878068 0.837 0.938 0 1 0 0.906
18 ZINC000011616636 0 1 1 1 1 1
19 ZINC000001916008 0 1 1 0 1 1
20 ZINC000100772345 0 0.999 0 1 1 0
21 ZINC38433168 0.982 1 0 0 0.052 0.993

NTP, U. S. National Toxicology Program; DTP, developmental toxicity potential.

NTP<0.3(noncarcinogen);>0.8(carcinogen).

Ames<0.3(nonmutagen);>0.8(mutagen).

DTP<0.3(nontoxic);>0.8(toxic).