Table 1. The baseline characteristics of patients with peripheral arterial disease, divided by ages (PAD) (N = 216).
| Parameters | Young (<65 y/o) (N = 81) | Old (≧65 y/o) (N = 135) | P value |
| Age (y/o) | 55.4 ± 8.3 | 76.2 ± 7.2 | 0.001 |
| Male gender, n (%) | 66 (81.4) | 73 (54.1) | 0.001 |
| BMI (kg/m2) | 26.1 ± 5 | 23.73 ± 3.9 | 0.001 |
| Heart rate (bpm) | 83.2 ± 16.5 | 80.4 ± 17.3 | 0.036 |
| SBP (mmHg) | 147.6 ± 29.7 | 156.2 ± 28.5 | 0.015 |
| DBP (mmHg) | 80.6 ± 14.5 | 75.3 ± 15.9 | 0.230 |
| Smoking, n (%) | 67 (82.71) | 70 (51.85) | 0.001 |
| Diabetes mellitus, n (%) | 46 (56.79) | 84 (62.22) | 0.47 |
| Hypertension, n (%) | 42 (51.85) | 106 (78.51) | 0.001 |
| CAD, n (%) | 38 (46.91) | 58 (42.96) | 0.45 |
| Heart failure, n (%) | 7 (8.641) | 20 (14.81) | 0.2 |
| Hyperlipidemia, n (%) | 37 (45.67) | 51 (37.77) | 0.25 |
| Previous stroke, n (%) | 9 (11.11) | 22 (16.2) | 0.32 |
| Cancer, n (%) | 4 (4.93) | 12 (8.88) | 0.42 |
| CKD (including H/D), n (%) | 15 (18.5) | 35 (25.9) | 0.05 |
| eGFR (ml/min/1.73m2) | 66.61 ± 35.9 | 52.48 ± 30.2 | 0.004 |
| ALT(mg/dl) | 25.1 ± 16.5 | 25.65 ± 32.8 | 0.906 |
| Total Cholesterol(mg/dl) | 162.1 ± 44.8 | 148.14 ± 44.8 | 0.119 |
| LDL(mg/dl) | 97.6 ± 38.2 | 86.32 ± 46.3 | 0.215 |
| Triglyceride (mg/dl) | 204.8 ± 24.9 | 156.34 ± 38.8 | 0.312 |
| Circulating STAT3 (ng/ml) | 17.7 ± 6.6 | 13.82 ± 6.2 | 0.001 |
| MALE, n (%) | 21 (25.9) | 53 (39.2) | 0.04 |
Data are n (%) or mean ± standard error; P < 0.05 as significance. Abbreviations: BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; CAD: coronary artery disease; CKD: chronic kidney disease; eGFR: estimated Glomerular filtration rate; ALT: Alanine aminotransferase; LDL: low-density lipoprotein; STAT3: Signal transducer and activator of transcription 3; MALE: major adverse limb events.