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. 2022 Jun 7;14(11):4728–4738. doi: 10.18632/aging.204106

Table 1. Comparison of clinical outcomes based on the retrieval or ovulation of DF at the time of retrieval with natural cycle IVF/M treatment.

Variable A B C P
No. of patients 377 54 34
Age of women, years 31.2 ± 4.0 30.9 ± 3.8 31.5 ± 4.1 0.803
FSH (mIU/mL) 5.72 ± 2.45 6.27 ± 2.55 6.23 ± 2.43 0.094
LH (mIU/mL) 3.20 ± 2.14 2.95 ± 2.33 3.09 ± 2.53 0.347
Estradiol (pg/mL) 41.59 ± 17.29 42.31 ± 21.69 41.09 ± 16.81 0.982
Progesterone (ng/mL) 0.55 ± 0.35 0.49 ± 0.2 0.56 ± 0.33 0.598
No. of oocyte retrieval cycles (%) 445 (83.0) 54 (10.1) 37 (6.9)
No. of completed ET cycles 441 52 35
No. of oocytes retrieved 4757 (10.7 ± 5.1) 501 (9.3 ± 4.7)* 354 (9.6 ± 5.1) 0.036
No. of oocytes retrieved from DF 465 (1.0 ± 0.2)
No. of mature oocytes retrieved 879 (2.0 ± 1.7) 69 (1.3 ± 1.3)* 39 (1.1 ± 1.5) * <0.001
No. of immature oocytes retrieved 3673 (8.3 ± 4.8) 408 (7.6 ± 4.3) 298 (8.1 ± 4.3) 0.528
Maturation rate 63.8 (2345/3673) 65.4 (267/408) 64.8 (193/298) 0.788
Fertilization rate 87.5 (2670/3052) 84.2 (266/316) 85.3 (191/224) 0.178
No. of embryos transferred 1246 (2.8 ± 0.7) 137 (2.5 ± 1.0)* 98 (2.7 ± 1.3) 0.038
Clinical pregnancy rate/ET cycle 34.5 (152/441) 34.6 (18/52) 25.7 (9/35) 0.571
Embryo implantation rate 15.2 (190/1246) 16.1 (22/137) 10.2 (10/98) 0.377
Cumulative live birth rate 69.1 (105/152) 66.7 (12/18) 66.7(6/9) 0.969
Singleton 88 (83.8) 10 (83.3) 6 (100.0%) 0.562
Twin 16 (15.2) 2 (16.7) 0
Triplets 1 (1.0) 0 0
Miscarriage rate/clinical pregnancy 27.0 (47/152) 33.3 (6/18) 33.3 (3/9) 0.969

Values are mean ± SD unless otherwise specified. Abbreviation: DF: dominant follicle. *Significant difference compared with Group A. Abbreviations: No: number; FSH: follicle-stimulating hormone; LH: luteinizing hormone.