Table 2. Multivariate Cox regression for PFI illustrating independent prognosis of IMRS3 and IMRS4.

	HR (95% CI)	P	HR (95% CI)	P
Age	1.004 (0.969-1.041)	.827	1.005 (0.969-1.042)	.791
Gender (Male vs Female)	0.737 (0.288-1.888)	.525	0.720 (0.282-1.835)	.491
Myasthenia gravis (Yes vs No)	0.671 (0.225-2.003)	.474	0.660 (0.221-1.970)	.456
WHO histology (B1-B3 vs A-AB)	1.675 (0.503-5.581)	.401	1.789 (0.538-5.946)	.343
WHO histology (C vs A-AB)	1.039 (0.174-6.222)	.966	0.981 (0.159-6.050)	.983
Masaoka's stage (III-IVB vs I-II)	0.924 (0.265-3.225)	.901	0.858 (0.245-3.003)	.811
TREM2hi	1.334 (0.733-2.429)	.346	1.310 (0.714-2.405)	.383
IMRS4/IMRS3	2.633 (1.226-5.657)	.013	2.921 (1.273-6.701)	.011