Table 5. Multivariate Cox regression for RFS and OS in an independent thymoma cohort.

	RFS		OS
	HR (95% C.I.)	P	HR (95% C.I.)	P
Age	1.024 (1.002-1.047)	.031	1.037 (0.997-1.079)	.069
Gender (Male vs Female)	1.387 (0.672-2.862)	.377	0.517 (0.160-1.666)	.269
Myasthenia gravis (Yes vs No)	1.592 (0.788-3.216)	.195	1.353 (0.428-4.274)	.607
WHO classification (C vs A-B3)	0.807 (0.371-1.754)	.588	1.810 (0.437-7.501)	.413
Masaoka's stage (III-IV vs I-II)	14.115 (2.740-72.723)	.002	1.739 (0.087-34.878)	.718
Adjuvant radiotherapy (Yes vs No)	3.450 (1.184-10.058)	.023	0.954 (0.073-12.457)	.971
Adjuvant chemotherapy (Yes vs No)	0.850 (0.235-3.070)	.804	1.34×10-5 (-)	.979
BRRS	2.212 (1.403-3.486)	.001	2.239 (0.886-5.662)	.089

The BRRS parameters in the table combine multiple biomarkers (including miR-130b-5p, miR-1307-3p, miR-425-5p, CD8, CD68 and CCL18).